The Perfect Lube for Conception , Seeking the Best Lubricant for Pregnancy? Look no further! Here are five key features to consider when choosing your fertility friendly lube. , 1 Conceive Plus Lubricant Fertility Support Gel HealthBoutiqueJo the health boutique Can your lube affect your chances of getting pregnant? Yes some lubricants can make it harder for sperm to reach the egg. Look for sperm safe or fertility friendly formulas that mimic your The most pregnancy friendly lubricants are the water based kinds. These lubes are water soluble, which means they dissolve in water. They're safer for you and your baby, typically because they contain fewer chemicals than Fertility Lubricant American Pregnancy Association